Multimodal Therapy of Advanced Cervical Cancer With Radiotherapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia
Who is this study for? Adult female patients with Stage IIB to IVA Cervical Cancer
Status: Recruiting
Location: See location...
Intervention Type: Radiation, Other, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The combination of radiation therapy or chemoradiation with Interstitial brachytherapy for advanced cervical cancer (pN+, FIGO-Stage II B - IV A is standard of therapy. The radio- and chemosensitive effect of an additional hyperthermia might improve the clinical outcome.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Histological confirmed carcinoma of the Cervix
• FIGO-Stage IIB-IVA; earlier stages when inoperable or according to patient's wish
• clinical M0; except: involvement of para-aortic lymph nodes
• Age ≥ 18 years
• ECOG ≤ 2
• Informed consent of the patient
Locations
Other Locations
Germany
Universitätsklinikum Erlangen, Strahlenklinik
RECRUITING
Erlangen
Contact Information
Primary
Oliver Ott, MD
st-studiensekretariat@uk-erlangen.de
++49 9131 85
Backup
Rainer Fietkau, MD
st-studiensekretariat@uk-erlangen.de
++49 9131 85
Time Frame
Start Date: 2017-08-01
Estimated Completion Date: 2099-12-31
Participants
Target number of participants: 999
Treatments
Experimental: Standard Arm
Radiation therapy: 50.4 Gy Brachytherapy: 35-40 Gy Chemotherapy: Cisplatin weekly 40mg/m\^2 (6 cycles) Hyperthermia: 10 times
Related Therapeutic Areas
Sponsors
Leads: University of Erlangen-Nürnberg Medical School